Raji Cell Assay
This assay, which is performed to detect the presence of circulating immune complexes, studies the Raji lymphoblastoid cell line. Identifying these cells, which have receptors for immunoglobulin G complement, helps to evaluate autoimmune disease.
Procedure and posttest care
Normal value is less than 13 mg AHG (antihemophilic globulin) Eq/ml.
A positive Raji cell assay can detect immune complexes, including those found in viral, microbial, and parasitic infections; metastasis; autoimmune disorders; and drug reactions. This test may also detect immune complexes associated with celiac disease, cirrhosis, Crohn's disease, cryoglobulinemia, dermatitis herpetiformis, sickle cell anemia, and ulcerative colitis.
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